By Admin 
Health News: Melanin is a very important pigment for our body which not only gives the skin its color but also protects it from ultraviolet rays of the sun. The amount of melanin in everyone’s body is different, it is found in abundance in people of countries living around the equator, on the other hand, as we move towards the polar regions, this amount decreases. Melanocytes are the cells that produce melanin. Like an onion, its skin also has many layers.
There are three layers of skin, the uppermost layer is called epidermis, the middle layer is called dermis and the lowest layer is called hypodermis. Melanin is formed at the junction of the upper layer of the skin, the epidermis, and the middle layer, the dermis. Keratinocytes and melanocytes are normally found in the epidermis. Melanocytes are cells that contain melanosomes that produce melanin. This melanin spreads throughout the body through keratinocyte cells which protect our body from ultraviolet rays of the sun.
Vitiligo causes white spots on the body and reduction in melanin production.
Vitiligo, leucoderma, white spots or spots, and white leprosy, apart from being a physical disease, also exists as a stigma in the society in which the patient develops white rashes on his hands and feet. According to a report, one out of every hundred people has vitiligo. In this disease, small white spots or big white spots appear on the person’s body. In this disease, melanocyte cells in the body die and melanin production stops. In some patients, along with swelling in the hands, the skin also becomes red and rough.
Vitiligo and Leucoderma: Causes, Differences and Side Effects of Modern Treatments
In common parlance, vitiligo and leucoderma are considered to be the same disease, but leucoderma is a disease caused by an accident whereas vitiligo is a type of auto immune disease. In leucoderma, some kind of injury to the skin is necessary, on the other hand, vitiligo can be caused by hormonal imbalance, allergy caused by deodorant, perfume or any chemical substance, repeated jaundice or typhoid, any more sensitive event, or by the use of anti-biotic medicines for a long time.
At times, the immune system itself starts destroying melanocytes unknowingly. The treatment of both is almost the same because pigmentation and immunity enhancing medicines are given in both, hence it becomes even more difficult to tell the difference.
The treatment given in modern medical systems is mostly in the form of steroids or to increase the immunity. These medicines also have a lot of side effects on the body. Many times due to this, skin cells start dying, or more hair starts growing on the skin, sometimes the complexion of the skin gets fine but it gets wrinkled and sometimes there is a burning sensation when exposed to sunlight.
Ayurvedic research in increasing cells and melanin production
To authenticate the herbs of this medicine made on the basis of ancient texts of Ayurveda, first of all, through high performance liquid chromatography technique, it was seen which are the signature phytometabolites which are directly helpful in curing melanin and their standardization was done. The first objective of this process was to discover those elements which are beneficial in these diseases according to Ayurvedic texts, secondly it was also necessary to ensure that whatever Ayurvedic medicine was being manufactured, all those elements were present in the right quantity.
Subsequently, tissues were prepared in the laboratory to test the cells and it was seen that this medicine was not causing any harm to the skin. Even with a Melanogrit dose of 100 micrograms/ml, it was observed that there was no harm to these cells. After that, it has also been observed that after giving melanogrit, the fiber like structures present inside these cells, which are called dendrites, are also expanding. These dendrites decide to what extent they can maintain their connectivity, so that melanin can be transported from one cell to another.
Skin color and cell health improvement with Melanogrit
After this, the authenticity of Melanogrit was confirmed through another research, for this it was found through Alpha-MSH (Alpha-Melanin Stimulating Hormone), which is a type of hormone and Ayurvedic herbal medicine Melanogrit, that if this hormone is first induced in healthy cells, then the color of the cells becomes black and then if the amount of this hormone is further reduced, then they become transparent, but with the use of Melanogrit, they can be restored to normal. Can be treated in the same form and color as healthy cells.
After that, an attempt was made to know its mode of action, in the research on tyrosinase, an enzyme which controls the level of L-dopa, it was found that with the use of melanogrit, cellular tyrosinase activity can also be increased, which proves that the functioning of the enzyme inside the skin cells has increased.
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