11 Jun 2025, Wed

Injections claiming to reduce obesity: The injections claiming to reduce obesity are not as effective as a clinical test in real life, because patients either stop taking them or reduce their doses. This has been revealed in a new research conducted in America. Doctors suggest more injections including vegovi and ozapic to patients suffering from type-2 diabetes, which are helpful in controlling blood sugar levels along with components like semaglutide or tirzeped.

What was taken out in research?

In research published in ‘Obesity Journal’, the researcher assessed the effect of anti-obesity injection in real life and controlling blood sugar. Dr. Hamlet Gasoyan, the chief researcher and a US -based Cleveland Clinic, said, “Our research shows that patients resorting to semaglutide or tirzeetide to overcome obesity are unable to lose as much weight as a clinical test in real life.”

He said, “According to our data, patients’ use of anti-obesity injections in real life after some time or reduce their dosage is the main reason.”

Research includes 7,881 adult patients

7,881 adult patients attended the research, whose average ‘body mass index (BMI)’ was above 39 i.e. they were facing “serious form of obesity”. Under BMI, the amount of body fat is estimated based on the length and weight ratio of the person.

One of the participants was in the ‘Pre-Diabetes Stage’ during the introduction of 1,320 research, which means that there was a higher risk of their type-2 diabetes. All the participants started taking an anti-obesity injection between 2021 and 2023 with semaglutide or tirzeetide.

The effect of blood sugar detected- Researcher

The researcher detected the weight of the participants and its effect on the level of blood sugar, one year after taking the injection. He found that the participants who stopped injections within three months reduced to 3.6 percent. At the same time, the weight of participants who stopped injections between three and 12 months decreased by an average of 6.8 percent.

The researcher said, “Averages were successful in weight loss 8.7 percent on an average, leaving injections (within three months), late closing (within three to 12 months) and a decrease of the participants who continued it even after a year,” the researcher said.

Research also found that patients who were suggested more doses of semaglutide or tirzeetide to control weight and blood sugar levels, their weight decreased by an average of 13.7 per cent and 18 per cent respectively.

Stop taking injection within 3 to 12 months

Talking about the participants with ‘pre-diabetes stage’, those who stopped taking injections within three months, 33 per cent of them remained normal blood sugar levels. At the same time, this figure was 41 percent among those who stopped injections within three to 12 months and 67.9 percent in the case of those who continued the injection.

Research also revealed that more than 20 per cent of the participants involved stopped injections within three months, while 32 per cent did so within three to 12 months. According to the researcher, factors such as the price of injection, insurance related reasons, side effects and market (injection) deficiency are included in the main reasons for stopping taking them.

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