1 Dec 2025, Mon


Foot Itching Liver Symptoms: Most people ignore the itching in hands and feet, considering it as dry skin, allergy or minor irritation. But if itching persists, there is no apparent reason, and there are no rashes on the skin, then it could be a sign of some major problem hidden inside the body. According to doctors, such itching on the palms and soles can be an early symptom of liver disease. When the functioning of the liver decreases, bile acids start accumulating in the body, which irritates the nerves of the skin and causes severe itching. If this itching increases at night, is not soothed by moisturizer or symptoms like fatigue and jaundice appear, then it is important to immediately consult a doctor.

Why do feet itch?

If the liver does not function properly, toxins and bile acids start increasing in the blood. These substances affect the nerves of the skin, causing intense and persistent itching in the palms and soles of the feet. This type of itching is called “cholestatic pruritus” and often occurs without a rash. This condition is often seen in several diseases, including primary biliary cholangitis, primary sclerosing cholangitis, and intrahepatic cholestasis of pregnancy. Why does itching occur in liver disease? Scientists told these hidden reasons

Scientists have not yet been able to determine any single reason for itching in liver related diseases. Experts believe that many different reasons work together behind this.

bile salt accumulation

When the liver becomes weak, bile salts are not able to be filtered properly in the body and start accumulating under the skin. This affects the nerves and can cause severe itching. However, it is also true that many people do not experience itching despite increased bile salts and some people feel itching even when the level is normal.

increased histamine

Increased levels of histamine are found in many patients suffering from liver-related itching. But the interesting thing is that antihistamine medicines often do not provide relief from it.

role of serotonin

Serotonin can increase the feeling of itching in the brain. Some research suggests that it intensifies the sensation of itching by affecting specific receptors of the nervous system. This is the reason why sometimes treatment of itching in liver disease becomes difficult.

Pregnancy or hormone therapy

Hormonal changes during pregnancy or while on hormone replacement therapy can increase itching. This has also been found to be associated with changes in the bile flow of the liver.

How to recognize itching related to liver?

According to a study published in the National Library of Medicine, if itching persists for more than six weeks, it comes under the category of chronic pruritus. There are some differences between common itching and itching caused by liver, such as

  • itching without rash
  • increases more at night
  • starting with hands and feet

Ways to reduce itching

  • Do not scratch the skin too much as it can cause infection.
  • If you have a habit of scratching at night, wear light gloves while sleeping.
  • Take bath with lukewarm or cold water, avoid hot water.
  • Use a humidifier in the room during cold weather.

Read this also- Daily Walking for Heart: How can just 30 minutes of walking improve heart health? Immediately follow these tips given by the surgeon

Disclaimer: This information is based on research studies and expert opinion. Do not consider this as a substitute for medical advice. Before adopting any new activity or exercise, please consult your doctor or relevant specialist.

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