Weight loss medicine: Sun Pharma’s new drug utriglutide, which is being developed to treat obesity and type-2 diabetes, has shown significant weight loss and metabolic improvements in post-menopausal women in early clinical studies. The results of the Phase 1a/2b trial of this drug were presented this week in the scientific session of the American Heart Association (AHA) held in New Orleans, USA. Utriglutide belongs to the same drug group as the world famous Monzaro and Vigovi. The specialty of these medicines is that they have become increasingly popular in India also. These medicines are GLP-1 receptor agonists, which work like liver hormones to reduce appetite.

What came out in the trial?

According to Sun Pharma, apart from weight loss, the drug showed improvement in several biomarkers related to systolic blood pressure, liver fat, and insulin sensitivity. Along with this, serum uric acid also reduced, which shows that the drug can affect many aspects of metabolic problems. Sun Pharma Chairman Dilip Shanghvi said, “Obesity and metabolic liver disease are on the rise, especially in post-menopausal women. The results of this initial study are encouraging and move us towards developing better treatments to combat these diseases.”

increasing problem

India’s anti-obesity drug market is currently worth Rs 3,000 to Rs 3,500 crore, which is expected to increase to Rs 25,000 crore by 2030. This was speculated to be due to the increasing problem of obesity and lifestyle diseases.

Study results give hope

This trial included post-menopausal women aged 52 to 69 years, who were suffering from obesity. After taking the drug for 14 weeks, those taking utriglutide lost an average of 8 percent weight and this continued until the 17th week. Those taking placebo lost only 2.1 percent and 1.2 percent weight, respectively.

What was seen till the 14th week?

• 76 percent women lost more than 5 percent weight.
• 25 percent women lost more than 10 percent weight.
• The average BMI initially was 43, which decreased to 39.7 to 39.8 by weeks 14 and 17.

The most important thing during this period was that there was a 28.6 percent reduction in liver fat, whereas only a 2.7 percent reduction was seen in the placebo group. These results show that this medicine can be helpful in problems like obesity as well as MASLD metabolic liver disease.

Side effect

If we talk about its side effects, they included loss of appetite, early fullness, nausea, indigestion and vomiting. Which are considered common among GLP-1 drugs. Dr. Rohit Loomba (UC San Diego), who was associated with the trial, said, “Utriglutide has shown significant improvement in liver fat and several metabolic parameters in women with obesity and MASLD, which is very encouraging.” If everything is approved after the trial, then this medicine can enter the market soon.

Read this also: World Diabetes Day 2025: Even if you don’t eat sweets, sugar level is increasing, know which habits increase the risk of diabetes?

Disclaimer: This information is based on research studies and expert opinion. Do not consider this as a substitute for medical advice. Before adopting any new activity or exercise, please consult your doctor or relevant specialist.

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Obesity and increasing weight have become the most serious problem for people today. Today’s unhealthy lifestyle and wrong habits of food are the biggest reason for this. Today every other person is a victim of this disease. Also, due to this obesity and increasing weight, many types of diseases also take home in the body. Many people do weight loss training to get rid of this problem. Calorie takes diet, do gym and workouts, but even after all this, there is no condition for many people. This is because they are doing this work by watching videos of weight loss challenge from Instagram and YouTube. Actually they do not know the right way of all these things. In such a situation, today we will tell you how you can reduce your weight easily, they should also stop drinking without food.

Due to weight gain

Before losing weight, it is most important to know why the weight actually increases. Actually, there can be many reasons behind obesity and weight gain such as eating more calories and fats, reducing physical work, slow metabolism rates and poor lifestyle etc. in the body etc. In such a situation, you have to fix all these things and fix them so that you can easily lose weight and do not wait back.

Weight loss tips

Low calorie food: The most effective way to lose weight is low calorie food. Often people get upset with obesity and stop drinking everything. But doing so is actually absolutely wrong. Doing this can cause weakness in the body. For weight loss, you only require eating low calorie food in your diet such as green leafy vegetables (spinach, celery), fruits (watermelons, berries), lean proteins (chicken breast, fish, eggs), Greek curd and grains etc.

Daily Exercise: Daily exercise can help you lose twice as fast. Exercise causes the body’s fat rapid loss and the metabolism rate is also better, which makes the food digest better, which does not increase obesity and you remain healthy.

Volume Eating: You can also lose weight rapidly through Walening Eating. Volume seating is a way in which you have to take low-calorie and high volume food. It maintains your calorie intake. This helps in weight loss and fat loss. People who feel hungry quickly are best for them because it makes you feel less hungry. In this, instead of eating calorie dens food, you take foods in which the amount of water is high. Such as fruits, vegetables and soup.

Healthy lifestyle: Along with weight loss, we should also pay great attention to the fact that we are back, do not do the weight. For this, it is very important to improve your lifestyle. This includes reducing stress, taking good sleep, eating balanced food and not consuming unhealthy things like cigarette-liquid.

Also read: Nail Marks Symptoms: This mark is visible above the nail, then understand this thing, there is a shortage of this thing, many gestures make our nails

Check out Below Health Tools-
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