Parkinson disease is a neurological disease. Now a big change is going to come in its identity and treatment. Recently in the research published in Nature Aging, it has been claimed that a new RNA-based blood test can be detected before the beginning of simples such as the problem of trembling or walking in hand and legs. That is, it will be easy for patients to diagnose on the initial stage itself.

How does blood test work?

This test is based on small fragments of TRNA (Transfer RNA). Earlier TRNA was linked to the process of making only protein, but now research found that its fragments can also give information about the disease.

Researchers get two special biomarkers

• Nuclear TRNA fragments, which are more in Parkinson patients.
• Mitochondrial TRNA Fragment, which is low in patients.

From the proportion of these two, it was found that the person is normal, on the initial stage or on the advance stage. The accuracy of this test came out 86 percent in a big study.

Why is this discovery special?

So far, Parkinson is detected only when I come to the Simpams. But this blood test:

• This is much cheaper than the rest of the treatments
• This will reveal the disease rapidly
• Apart from this, only blood samples (minimly-invasive) test process.

This test can be effective for those who have a high risk of Parkinson, eg, erasure to end genro disease, REM Sleep Disorder or Smell.

FDA approval and future

There will be more trials on this test right now. But recently FDA has approved the blood test for Alzheimer’s Disease, which is expected that the Parkinson test may also get approval quickly. In the future, this test can be useful not only to diagnose but also to track disease progress and to see the effect of treatment. If all goes well then this test routine can become a part of health checkup. Researchers believe that this test will be tested on a large scale in the coming time. Also, it will be made more accurate by adding more biomarkers to it. It can become a powerful diagnostic tool in combination with future genetic testing and brain imaging.

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