How GLP-1 Medicines Help Reduce Weight: The case of obesity is increasing rapidly, it is causing all kinds of diseases. That is why WHO has taken a big step to deal with the rapidly increasing problem of obesity across the world. WHO has clearly stated for the first time that the new generation weight loss drugs GLP-1 therapy can play an important role in reducing obesity. These medicines include famous brands like Ozempic and Monjaro, which have become very popular in recent years.

According to WHO, obesity is no longer just a lifestyle issue, but a chronic and re-lapsing disease, which requires long-term treatment and care. Therefore, the organization has advised that long-term use of GLP-1 drugs should be considered for the treatment of obesity in adults. However, pregnant women have been kept out of this.

dangerous levels of obesity

In 2022, more than 37 lakh people died due to diseases related to obesity or increased weight. This number is more than the total deaths of malaria, TB and HIV combined. WHO estimates that if the situation does not change, the number of obese people in the world will double by 2030. WHO chief Dr. Tedros Adhanom says, “Obesity is a global health challenge. Medicines alone cannot end this crisis, but GLP-1 therapy can help millions of people reduce obesity and its associated risks.” However, WHO also said that more data is still needed on the long-term effects and safety of these medicines.

GLP-1 therapies are changing #obesity care. What does WHO recommend?

Here’s what you need to know. pic.twitter.com/e7EuEmeqxL

— World Health Organization (WHO) (@WHO) December 1, 2025

Not a magical cure, but an important weapon

WHO says that GLP-1 drugs should not be seen as medicines alone, but should be combined with many things including-

• better eating habits
• regular physical exercise
• behavior modification

What do experts say?

Dr. Shailesh Jena, an endocrinologist at Shaheed Hospital in Raipur, says that this new guideline of WHO is a step taken in the right direction. According to him, “GLP-1 drugs have given better results than expected in the treatment of obesity. These drugs control appetite, improve metabolism and increase insulin sensitivity. In such a situation, they can prove to be a great help for patients on whom the effect of diet and workout is limited.” According to Dr. Shailesh Jena, obesity is not a simple problem of weight gain, but a metabolic disorder in the body, which needs long-term management.

Also read: Childbirth Lifespan: Does the mother’s age decrease after giving birth to a child? Shocking revelation in research

Disclaimer: This information is based on research studies and expert opinion. Do not consider this as a substitute for medical advice. Before adopting any new activity or exercise, please consult your doctor or relevant specialist.

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Weight Loss Drugs: Amidst the rapidly increasing obesity in India, the trend of weight loss medicines has also increased. Instead of gym and dieting, people are now taking the help of such medicines which help in reducing weight. However, doctors are constantly warning about the side effects of these medicines. In such a situation, let us know today which medicines are being used for weight loss in India, along with which are the most dangerous medicines?

Most of Objeta-60 Capsules

Objeta-60 Capsule is one of the most commonly used medicines to reduce obesity. This medicine prevents the absorption of fat in the body, which reduces calorie intake and gradually leads to weight loss. This medicine is taken with food or within 1 hour of food during the day. Doctors believe that if it is taken with regular exercise and a balanced diet, its results are better. However, it also has many side effects. The use of this medicine may cause problems like stomach ache and diarrhea in many people. In some cases, gas problems may also occur. Taking this medicine for a long time without doctor’s advice can be more dangerous.

Mounjaro and Zepbound

American company Eli Lilly’s drugs Monjaro and Zepbound were recently approved in India for weight loss and diabetes control. The chemical name of both these medicines is Tirzepatide. This medicine is given in the form of injection which controls insulin in the body and also reduces appetite. According to doctors, this medicine activates GLP-1 and GIP hormones in the body, due to which the person feels full and eats less. At the same time, this medicine can also have many side effects. Taking this medicine includes problems like vomiting, nausea, dizziness and low blood sugar level. Apart from this, this claim can prove to be very dangerous for people who have a history of thyroid cancer.

Vegovi recently launched drug

Vegovi drug manufactured by Danish company Novo Nordisk was also recently launched in India. This medicine is given in the form of injection to reduce weight in severe cases of obesity. This medicine activates the appetite suppressing hormone GLP, due to which the person eats less and gradually starts losing weight. This medicine can also have many side effects, which include vomiting, nausea, stomach pain and gas problems.

Balloon Capsule Treatment

Now people are also turning to balloon capsule treatment for weight loss. It is a capsule which swells like a balloon after entering the stomach and reduces the space in the stomach. Due to this the person eats less food and starts losing weight. It is used through endoscopy or swallow pill method. However, this method is expensive, its one-time treatment costs between Rs 2.5 lakh to Rs 4 lakh. At the same time, this treatment is not for those people who have problems with heartburn or reflexes.

Which medicine is the most dangerous?

According to doctors, medicines like Monjaro, Zepbound and Vegovi are effective, but their side effects can be more serious than other medicines. If they are used without doctor’s supervision, there can be major problems related to blood sugar level, thyroid and digestion in the body. In many cases, more serious problems can also be seen due to these medicines.

Also read- Wrong eating habits can affect eyesight, avoid these things today itself.

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Weight Loss Drugs Heart Attack: In today’s time, if you ask people what is the biggest problem for them, then most of their answers will be about obesity. People of all ages are troubled by this. Due to the changing lifestyle and lack of exercise, this disease is spreading very fast. People are using medicine a lot to reduce it or to avoid it. Let us tell you whether a heart attack comes quickly from this medicine to lose veg or all this is a saying. Know the truth.

What is the effect?

Some time ago a research was conducted in America, in which research was done about ozapic medicine. According to media reports, it was revealed that this drug is very helpful for humans in VAT loss as well as heart diseases. This complete research was done by the doctors of the dick group ‘Mass General Brigham’, the result of which caught the attention of the whole world. It was told that this medicine proved to be very helpful for those who already have heart problems. After using them, he got very little to go to the hospital. During this entire research, the two medicines which were given the most attention were Semaglutide and Tirjeetide. The researcher included 90,000 people throughout the research, including symptoms of heart failure, obesity and type-2 diabetes.

Does a heart attack come from this medicine?

According to the doctors of ‘Mass General Brigham’, the perception is now outstanding that the drug to reduce obesity increases the risk of heart attack. Research revealed that due to taking semaglutide, the chances of early death in patients or the hospitalization were reduced by 42 percent, while the impact of Tirjeetide was also much higher. After its use, this percentage increased to 58. However, if you take the medicine to lose VAT, then the most noteworthy thing is that the drug should be real or should be of brand, using any medicine can increase the risk. Some old medicines that could cause heart attack have been removed from the market. If you are going to use weight loss medicine, then please consult a doctor once.

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Disclaimer: This information is based on the opinion of research studies and experts. Do not consider it an alternative to medical advice. Before adopting any new activity or exercise, consult your doctor or concerned specialist.

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New generation medicines being used to reduce diabetes and obesity are nowadays worldwide discussion. They are known as ‘Blockbuster Weight Loss Drugs’. But do you know that these medicines can affect your eyes health? Recently, two new studies, published in Jama Network Open, have revealed this, after which a debate has started around the world whether it is really harmful to our eyes.

What medicines are in discussion?

Semaglutide: It is a GLP-1 hormone-like medicine, which controls blood sugar and reduces appetite. It is used for type-2 diabetes and weight loss.

Tirzepatide: It also acts like a gip hormone with GLP-1, which helps insulin release and weight control.

Which eye diseases are threatened?

These drugs have been linked to two serious eye problems in studies:

Diabetic retinopathy: Due to excess blood sugar for a long time, the vein of the retina deteriorates, which can lead to blindness.

Naion (non-arteritic anterior ischemic optic neuropathy): Suddenly, without pain, vision loss can occur due to reduced blood flow in the vein of the eye.

What came out in research?

In the first study, in patients with type-2 diabetes, GLP-1 drugs were compared to those taking other medicines. As a result, the risk of diabetic retinopathy and naion was found slightly higher than GLP-1 drugs. The good thing is that these drugs were less at risk of total blindness and the possibility of serious problems of retinopathy also declined.

In the second study, the most powerful GLP-1 drugs (semaglutide, tirzepatide) were found to be slightly increased cases of NAION and other optic nerve disorders. Both these studies have forced people to think once again.

Why was research needed?

If you talk about why it was needed, then there were indications of increasing the risk of diabetic retinopathy in the initial trial of Semaglutide about 10 years ago. After this, high-risk patients were kept out of further trial and monitoring was increased. Recently, two major research was done after the NAion case increased in a study. According to the European Medicine Agency, about 1 out of every 10,000 people who take semaglutide can have Naion. A similar study is also necessary for tirzepatide.

Should the medicine stop taking?

Experts say no. These drugs are a gamechanger in the management of diabetes and obesity. Also, their positive effects have been seen on heart, kidney and liver health.

What are the things to keep in mind?

• People who already have diabetic retinopathy must check the eyes before and after increasing the dose.
• Increase the dose gradually so that there is no sudden change in blood sugar.
• Keep better coordination between diabetes doctor and i-specialist.
• Eye safety should also be included in all future GLP-1 drug trials.

These medicines are very effective in weight and blood sugar control, but it is necessary to be cautious for the health of the eyes. From time to time, you can take their benefits with checkup and correct monitoring and reduce the risk.

Also read- You are not taking excessive vitamin D, know how much danger to kidney and heart?

Disclaimer: Some information given in the news is based on media reports. Before implementing any suggestion, you must consult the concerned expert.

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