17 Jan 2026, Sat

In today’s time, IVF (In Vitro Fertilization) has become the biggest ray of hope for those couples who have been dreaming of becoming parents for a long time. When IVF is resorted to after years of efforts, treatments, medicines and emotional ups and downs, expectations run high. Doctors say that the eggs are good, the sperms are fine, the embryo is beautiful, the uterus is also ready, yet when the report comes negative, only one question echoes in the mind, when everything was perfect, then why did IVF fail.

IVF is not a process that works like a machine. It is a combination of body, hormones, genetics and mental state. Many times everything looks fine from outside, but somewhere inside there is a small problem hidden, which does not allow the pregnancy to progress. In such a situation, let us know why IVF fails even after everything is perfect.

How to recognize symptoms of IVF failure?

In IVF, about 14 days after embryo transfer are very important. This is called two-week wait. During this time, women take medicines like progesterone, due to which pregnancy-like symptoms can be felt, whether there is pregnancy or not. But there are some signs which may indicate IVF failure. For example, if you start bleeding like normal periods a few days after embryo transfer, it may mean that the embryo could not stick to the wall of the uterus.

Home tests may show anything, but the most reliable test in IVF is the beta-HCG blood test. If the hormone level does not increase, then the IVF cycle is considered failed. If earlier you were feeling heaviness in the breasts, mild stomach ache or fatigue and suddenly all this ends, then it could be a sign that the production of pregnancy hormones has stopped. In such a situation, keep in mind that do not stop the medicines without consulting the doctor, because in some cases the pregnancy continues despite bleeding.

Why does IVF fail even after everything is perfect?

1. Of the embryo – Sometimes the embryo looks very beautiful, but there may be genetic problems inside it. Such embryos either do not stick or get spoiled quickly. This is considered to be the most common reason for IVF failure.

2. Layer of uterus – If the endometrium i.e. the inner layer of the uterus is very thin (less than 7 mm), weak or not ready at the right time, then the embryo does not get nutrition and implantation fails.

3. Internal problems of pregnancy – Adhesions formed due to fibroids, polyps, cysts or old surgeries can also hinder the attachment of the embryo.

4. Lack of blood flow – If the blood flow to the uterus is not proper, then the embryo does not get the necessary oxygen and nutrition.

5. Infection or TB – If there is a chronic infection (such as TB) in the uterus or tubes, dirty fluid accumulates in the tubes, which can prove poisonous to the embryo.

6. Increasing age – After 35 years, both the number and quality of eggs start decreasing. This increases the risk of genetic defects.

7. Lifestyle and stress – Obesity, smoking, poor diet and excessive stress reduce the success of IVF to a great extent.

8. Immune system problems – In some women, the body’s immune system considers the embryo to be a foreign object and attacks it, due to which implantation fails.

9. Negligence in medicines – Not taking medicines on time or not following doctor’s advice properly can also be a major reason for IVF failure.

Also read: Heart Attack After Stent: Why do heart veins get blocked even after stent insertion? understand with doctor

Disclaimer: This information is based on research studies and expert opinion. Do not consider this as a substitute for medical advice. Before adopting any new activity or exercise, please consult your doctor or relevant specialist.

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