Weight loss medicine: Sun Pharma’s new drug utriglutide, which is being developed to treat obesity and type-2 diabetes, has shown significant weight loss and metabolic improvements in post-menopausal women in early clinical studies. The results of the Phase 1a/2b trial of this drug were presented this week in the scientific session of the American Heart Association (AHA) held in New Orleans, USA. Utriglutide belongs to the same drug group as the world famous Monzaro and Vigovi. The specialty of these medicines is that they have become increasingly popular in India also. These medicines are GLP-1 receptor agonists, which work like liver hormones to reduce appetite.

What came out in the trial?

According to Sun Pharma, apart from weight loss, the drug showed improvement in several biomarkers related to systolic blood pressure, liver fat, and insulin sensitivity. Along with this, serum uric acid also reduced, which shows that the drug can affect many aspects of metabolic problems. Sun Pharma Chairman Dilip Shanghvi said, “Obesity and metabolic liver disease are on the rise, especially in post-menopausal women. The results of this initial study are encouraging and move us towards developing better treatments to combat these diseases.”

increasing problem

India’s anti-obesity drug market is currently worth Rs 3,000 to Rs 3,500 crore, which is expected to increase to Rs 25,000 crore by 2030. This was speculated to be due to the increasing problem of obesity and lifestyle diseases.

Study results give hope

This trial included post-menopausal women aged 52 to 69 years, who were suffering from obesity. After taking the drug for 14 weeks, those taking utriglutide lost an average of 8 percent weight and this continued until the 17th week. Those taking placebo lost only 2.1 percent and 1.2 percent weight, respectively.

What was seen till the 14th week?

• 76 percent women lost more than 5 percent weight.
• 25 percent women lost more than 10 percent weight.
• The average BMI initially was 43, which decreased to 39.7 to 39.8 by weeks 14 and 17.

The most important thing during this period was that there was a 28.6 percent reduction in liver fat, whereas only a 2.7 percent reduction was seen in the placebo group. These results show that this medicine can be helpful in problems like obesity as well as MASLD metabolic liver disease.

Side effect

If we talk about its side effects, they included loss of appetite, early fullness, nausea, indigestion and vomiting. Which are considered common among GLP-1 drugs. Dr. Rohit Loomba (UC San Diego), who was associated with the trial, said, “Utriglutide has shown significant improvement in liver fat and several metabolic parameters in women with obesity and MASLD, which is very encouraging.” If everything is approved after the trial, then this medicine can enter the market soon.

Read this also: World Diabetes Day 2025: Even if you don’t eat sweets, sugar level is increasing, know which habits increase the risk of diabetes?

Disclaimer: This information is based on research studies and expert opinion. Do not consider this as a substitute for medical advice. Before adopting any new activity or exercise, please consult your doctor or relevant specialist.

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Weight loss drugs: Obesity worldwide is causing serious health problems. Today every other person is seen following some medicine, exercise or diet plan for his increasing weight. If we talk about India, then the situation is worse. According to the recent National Family Health Survey report, one in every four is a victim of adult obesity and overweight. For the last few years, this figure seems to be increasing even faster.

Due to obesity in India, people are becoming more dependent on the weight loss drugs found in the market to lose weight. In such a situation, let us know how this market of weight loss drug is spreading in India.

Increasing obesity problem in India

Obesity is becoming increasingly one of India’s most serious problems. Many recent surveys show that this health problem is not only the elders but also children are falling prey to it. According to the National Family Health Survey, 24% of Indian women and 23% of Indian men are either overweight or are very thick. Even more worrying is that the number of children weighing over five years of age has increased from 2.1% to 3.4% in just five years. Apart from this, all adults in one of every five Indian homes are overweight or thick.

Market of weight loss drugs in India

In view of the increasing rate of obesity, many big companies have launched different medicines to reduce obesity. In this episode, in March 2025, Eli Lily launched her obesity reducing drug Maunzaro (Tirjeetide). This medicine is easily available in the markets in single dose after getting approval from CDSCO. The sale of this medicine is increasing very fast. Initially, its sales stood at Rs 24 crore and in June 2025, the figure rose to Rs 50 crore. The medicine of silence is very expensive. Its 2.5 ml of gram vial is priced at Rs 3,500 and 5 ml gram vial is Rs 4,375.

Why demand is increasing

Actually, these medicines given to reduce obesity are actually given to treat type 2 diabetes. These drugs are also becoming increasingly popular due to the benefits of their weight loss. Actually, after eating food, GLP-1 and GIP hormones are released to control the level of blood sugar in the body, after which GLP-1 makes people feel full and reduces their appetite. This formula helps in losing weight. In such a situation, medicines like silence and ozapic help to lose weight by mimicking these hormones.

How to deal with overweight and increasing obesity

To deal with obesity and overweight, it is very important for people to be aware of health. Daily exercise, yoga and balanced food is effective to eliminate this problem from the root. Also, people should do more physical work. Apart from this, this disease can be relieved only by eliminating the addiction of packed and processed food.

Also read: Hand Tremors: In which disease the hands start trembling in youth, know how dangerous they are?

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Nowadays weight gain and diabetes problem has become common. In such a situation, everyone is looking for an effective and safe way. Ecnoglutide is a new drug, which helps in losing weight and controlling blood sugar. It acts like drugs like ozmpic and wegovy, but its results look better than all drugs so far. Let us tell you how it can be beneficial for you and what has come out in research so far.

Clinical trial results

In the Phase 3 trial held in China, 621 diabetes patients between 18 and 75 years were tested. All the patients were taking metformin together. The trial showed that those taking ecnoglutide reduced almost twice more weight than people with dulaglutide.

Specialty

The biggest thing about ecnoglutide is that it targets the Camp Pathway. It controls body weight and metabolism properly. The rest of GLP-1 drugs affect many routes, which can lead to more side effects. But this is not in ecnoglutide, so the effects are better and less side effects.

Not only weight, health is also better

Taking ecnoglutide reduced the waist and Hip size, reduced triglycerides, which are very important for heart and body health. This means that it is not just weight loss drug, but is a drug benefiting the entire metabolic system. In this way, it is proving to be better effective than the rest of the dogs.

Side effects and safety

This drug was well talked by the patients. Some people had light side effects like nausea and diarrhea, but they were reduced over time. Researchers said that even in low dose, it is more effective than dulaglutide. This could reveal its benefits.

Researchers say

“Ecnoglutide takes up weight, waist, hip and triglycerides. This may be drug type 2 diabetes and a new and effective option to lose weight.”

What is expected in the future

If further trials are also successful, then ecnoglutide can become a game-changer for weight loss and diabetes control. It not only reduces weight but is also beneficial for heart and body health. However, after coming to the market, it will be known how beneficial it will be.

Also read- This cancer that is spreading rapidly in youth, know its symptoms, danger and way of escape

Disclaimer: Some information given in the news is based on media reports. Before implementing any suggestion, you must consult the concerned expert.

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Ozapics are also known as Semaglutide. Actually, Type-2 is a medicine made for diabetes patients. It controls blood sugar level in our body, but for some time people have also been using it a lot to lose weight. Actually, in some research, it was said to be beneficial to lose weight. However, now a new and worrying thing has come to light about this medicine.

People’s mood and personality are also affecting the consumption of ozapics. Complaints like mood swings and personality disorder are being received as its side-effects, which are not sure to be right for health. Due to its indiscriminate use, new threats are now coming out. In this article, experts are telling what is an ozemic, is it safe and there are no side effects.

What is Ozapic?

The Ozamic was approved for type 2 diabetes patients above 18 years of age from American FDA in 2017. Wet loss expert Dr. Reema Arora says that this is an injection, which is applied once a week on the advice of a doctor and it works to increase insulin in the body. However, it has not been officially approved for weight loss, but then doctors write it many times.

This medicine acts like a natural hormone made in the body. When the level of hormone increases, they send a signal to the brain to fill the stomach. It also slows down the digestion of food, which digss the food late, which gives some effect to some extent as bariatric surgery. Ozapics are used for a long time in the treatment of diabetes and weight loss is a common side effect.

Ozapic Treatment: Risk and Benefits

Expert Dietician Aarti Jain says that the use of ozapic should always be in the strict supervision of the doctor. Using without supervision can lead to serious health risk and side effects.

• Back to weight re -weight: Many users experience the weight again after closing the medicine. This is probably because the body adopts and increases hunger.
• Gastrointestinal problems: Common side-effects include nausea, vomiting, diarrhea and constipation, as this drug slows down digestion.
• Risk of hypoglycemia: There is a risk of sudden decline in blood sugar (hypoglycemia), especially if it is taken with another diabetes medicine.

Rare and Serius

• Side-effects: Although these are uncommon, there is a mild risk of pancretitis and even some thyroid tumors. Other general side-effects may include dizziness, headache and fatigue.
• Muscle loss: Without proper diet and exercise, some individuals may have an experience of muscle deficiency while taking ozapics.
• Not for everyone (not for everyone): Despite weight loss benefits, this is not a universal solution of Obesity. Doctors prescribe it on the basis of specific medical criterion of diabetes or obesity, not just for cosmetic weight loss.

Ozapic is an effective medicine when it is used for the right purpose and in a proper manner. However, it requires careful medical guidance to reduce potential risk and to control patient safety.

Also read: How much alcohol starts to reduce age? The shocking figure finally came out

Disclaimer: Some information given in the news is based on media reports. Before implementing any suggestion, you must consult the concerned expert.

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