By Admin 
Statins absolute show Reduction: Often when a person’s cholesterol level comes on “borderline”, doctors recommend taking the medicine. But when many people look deeply, they feel that the risk of heart attack or death from statin can decrease by 50 percent, while in reality this figure is quite different. Let’s understand.
What is Absolute Risk and Relative Risk?
Relative Risk Reduction (RRR) means how much danger in the relationship decreased.
Absolute Risk Reduction (Arr) means how much your real danger (RISK) decreased.
That is, the effect of the statin is not the same for everyone on any percentage. It depends on how big the risk of your early disease is.
On what things are the risk of heart disease?
Doctors count your risk from many factors,
- Age
- gender
- Blood pressure
- Cholesterol level (total and HDL)
- Smoking habit
- History of family
Other diseases
If someone already has heart disease, then the status is very high and the need for calculation is also less. But for those who do not have heart disease right now, doctors calculate every risk by adding every risk.
Understand by example
First case
75 -year -old male, cholesterol 220 mg/dl, HDL 45 mg/dl and blood pressure 140/80 mmhg.
According to the calculator, the risk of heart disease in the next 10 years = 19.4 percent.
If he takes the statin, the risk will be reduced by about 20 percent. That is, now there will be danger = 15.5 percent
This means Absolute Risk Reduction = 3.9 percent.
Second case
50 -year -old woman, all other figures the same.
Calculator shows that risk in the next 10 years = 3.6 percent
It will be 20 percent less than taking a statin, ie new risk = 2.88 percent
Absolute Risk Reduction = only 0.72 percent
What is Number Needed to Treat (NNT)?
Doctors and scientists use another scale, which is called NNT (Number Needed to Treat).
This means how many patients should be given medicine, so that an incident (heart attack or death) can be stopped in 10 years.
In the first case given above, about 26 men will have to give 10 years of statin so that a heart attack can be stopped.
In the second case, about 139 women will have to be given medicines so that a case can be stopped.
Is it beneficial to take a statin?
It completely depends on how much your real risk is.
If your risk is high, then Absolute Risk Reduction will also be high and the benefit will look big.
If the risk is low, then the effect of the drug will also look smaller
The price of the statin medicine ($ 5–10 per month) is not very high and serious side effects are rarely seen. But still, taking or not taking medicine depends entirely on the thinking of the person and the advice of the doctor. The statin medicine helps in reducing the risk of heart disease, but its real effect is different on individual person. This is the reason why doctors decide who needs medicine by calculating Absolute Risk and Relative Risk and who does not.
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Disclaimer: This information is based on the opinion of research studies and experts. Do not consider it an alternative to medical advice. Before adopting any new activity or exercise, consult your doctor or concerned specialist.
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